ETF comparison
IBBvsXLV
Both Healthcare.
iShares Biotechnology ETF · State Street Health Care Select Sector SPDR ETF
Holdings overlap
9 positions appear in both funds. Buying equal dollars of IBB and XLV would leave roughly11.1%of each dollar exposed to the same underlying securities.
Side by side
Sub-score comparison
Tracking quality isn't part of the composite — seewhat we don't scorefor why.
Cost difference
XLV is 36 bps cheaper than IBB. On a $100,000 position that's about $360/yr more in fees for IBB.
Fee figure is the annual expense charged on $100,000. To see how the gap compounds over a multi-decade holding period, open thecost calculator pre-filled with IBB vs XLV.
Top shared holdings
9 shared in total| # | Holding | In IBB | In XLV | Overlap |
|---|---|---|---|---|
| 1 | Amgen, Inc. | 7.83% | 3.40% | 3.40% |
| 2 | Gilead Sciences, Inc. | 6.84% | 2.73% | 2.73% |
| 3 | Vertex Pharmaceuticals, Inc. | 8.08% | 2.19% | 2.19% |
| 4 | Regeneron Pharmaceuticals, Inc. | 4.91% | 1.08% | 1.08% |
| 5 | Biogen, Inc. | 2.47% | 0.56% | 0.56% |
| 6 | Moderna, Inc. | 1.98% | 0.43% | 0.43% |
| 7 | Incyte Corp. | 1.75% | 0.33% | 0.33% |
| 8 | Bio-Techne Corp. | 0.86% | 0.19% | 0.19% |
| 9 | Charles River Laboratories International, Inc. | 0.84% | 0.19% | 0.19% |
Only in IBB
241 total- BlackRock Funds III11.66%
- Argenx SE3.76%
- Alnylam Pharmaceuticals, Inc.3.12%
- Natera, Inc.2.89%
- Revolution Medicines, Inc.2.78%
- Illumina, Inc.2.07%
- Insmed, Inc.1.78%
- BeOne Medicines Ltd.1.77%
- United Therapeutics Corp.1.73%
- Roivant Sciences Ltd.1.43%
Only in XLV
52 total- Eli Lilly & Co16.51%
- Johnson & Johnson10.64%
- AbbVie Inc7.74%
- UnitedHealth Group Inc6.57%
- Merck & Co Inc5.52%
- Thermo Fisher Scientific Inc3.24%
- Abbott Laboratories2.75%
- Intuitive Surgical Inc2.45%
- Pfizer Inc2.39%
- CVS Health Corp2.30%
Open IBB or XLV at a brokerage
Both funds trade commission-free at major US brokerages.
Affiliate links — opening an account through these earns PlainIndex a one-time referral. Scoring is computed before any affiliate consideration; see our methodologyand funding disclosure.
Holdings overlap is the sum of min(weight_a, weight_b) over positions matched on ISIN (CUSIP fallback). Methodology: see/methodology/.
Comparing two funds doesn't endorse swapping one for the other. Tax-lot history, account type, and personal goals matter — PlainIndex publishes data and methodology, not investment advice.