Skip to main content

iShares Biotechnology ETF

iShares · Tracks NYSE Biotechnology Index · Inception Feb 5, 2001

Expense ratio
0.44%
44.0 bps
Net assets
$11.20B
TTM yield
0.16%
Last price
$207.74
as of Oct 23, 2026
Avg volume
1,703,650
shares/day, 30d

Trailing returns

through Oct 23, 2026
1 year
+31.7%
3 year
+22.9%
annualized
5 year
+5.9%
annualized
Growth of $1, 2021-11 to 2026-10

Price return from month-end closes, distributions reinvested at month end. Excludes trading costs, bid-ask spreads and taxes. Past performance says nothing about future returns and is not part of the composite score — see the methodology for what the score does measure.

Composite score

72 / 100
Cost 56

Based on a 0.44% expense ratio.

Liquidity 100

Based on $11.20B in net assets.

Concentration 50

Top-10 holdings represent 44.7% of net assets.

Tax efficiency 85

Healthcare base · ETF wrapper · 0.16% TTM yield.

The composite is a weighted average of the four core sub-scores above (cost, tax efficiency, liquidity, concentration). Missing sub-scores fall back to the per-category median when the category has at least 50% data coverage, so funds without (e.g.) parsed N-PORT holdings aren't accidentally boosted by renormalization. Tracking quality is shown where computable but isn't currently part of the composite weighting. See methodology for formulas, the tracking-quality partial-coverage rationale, and the dimensions we deliberately don't score (methodology v0.5.2).

Look through IBB, or compare the fee

Top holdings

250 total holdings · as of Jun 30, 2026
# Holding Weight
1 Vertex Pharmaceuticals, Inc. 8.08%
2 Amgen, Inc. 7.83%
3 Gilead Sciences, Inc. 6.84%
4 Regeneron Pharmaceuticals, Inc. 4.91%
5 Argenx SE 3.76%
6 Alnylam Pharmaceuticals, Inc. 3.12%
7 Natera, Inc. 2.89%
8 Revolution Medicines, Inc. 2.78%
9 Biogen, Inc. 2.47%
10 Illumina, Inc. 2.07%

Compare IBB with another fund

Or skim the closest-overlap funds below.

Similar ETFs by holdings overlap

Open IBB at a brokerage

Affiliate links — opening an account through these earns PlainIndex a one-time referral. Scoring is computed before any affiliate consideration; see our methodology and funding disclosure.

Holdings sourced from SEC Form N-PORT-P (accession 0002071691-26-019768).