ETF comparison
FHLC vs XBI
Both Healthcare.
Fidelity MSCI Health Care Index ETF · State Street SPDR S&P Biotech ETF
Holdings overlap
117 positions appear in both funds. Buying equal dollars of FHLC and XBI would leave roughly 12.6% of each dollar exposed to the same underlying securities.
Unmatched is the part of a fund's weight the other fund doesn't match: names only it holds, plus any extra weight it puts in names both funds hold.
Side by side
Sub-score comparison
Tracking quality isn't part of the composite — see what we don't score for why.
Cost difference
FHLC is 27 bps cheaper than XBI. On a $100,000 position that's about $266/yr more in fees for XBI.
Fee figure is the annual expense charged on $100,000. To see how the gap compounds over a multi-decade holding period, open the cost calculator pre-filled with FHLC vs XBI.
Top shared holdings
117 shared in total| # | Holding | In FHLC | In XBI | Overlap |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals Inc | 1.76% | 1.06% | 1.06% |
| 2 | AbbVie Inc | 6.42% | 1.04% | 1.04% |
| 3 | Amgen Inc | 3.00% | 0.99% | 0.99% |
| 4 | Gilead Sciences Inc | 2.34% | 0.96% | 0.96% |
| 5 | Regeneron Pharmaceuticals Inc | 1.15% | 0.96% | 0.96% |
| 6 | Natera Inc | 0.52% | 1.16% | 0.52% |
| 7 | Revolution Medicines Inc | 0.44% | 1.20% | 0.44% |
| 8 | Biogen Inc | 0.43% | 1.03% | 0.43% |
| 9 | Alnylam Pharmaceuticals Inc | 0.39% | 0.96% | 0.39% |
| 10 | Insmed Inc | 0.30% | 1.08% | 0.30% |
| 11 | United Therapeutics Corp | 0.30% | 0.92% | 0.30% |
| 12 | Incyte Corp | 0.29% | 1.00% | 0.29% |
Only in FHLC
217 total- Eli Lilly & Co 13.35%
- Johnson & Johnson 8.93%
- UnitedHealth Group Inc 5.44%
- Merck & Co Inc 4.66%
- Thermo Fisher Scientific Inc 3.09%
- Abbott Laboratories 2.66%
- Pfizer Inc 2.06%
- Bristol-Myers Squibb Co 1.93%
- CVS Health Corp 1.92%
- Intuitive Surgical Inc 1.82%
Only in XBI
39 total- Summit Therapeutics Inc 1.01%
- Nuvalent Inc 0.93%
- Catalyst Pharmaceuticals Inc 0.87%
- Absci Corp 0.56%
- Hyperliquid Strategies Inc 0.46%
- Avalo Therapeutics Inc 0.35%
- Vor BioPharma Inc 0.30%
- Replimune Group Inc 0.28%
- Solid Biosciences Inc 0.24%
- Rigel Pharmaceuticals Inc 0.24%
Related comparisons
More comparisons with FHLC
- FHLC vs VGT · Vanguard Information Technology Index Fund ETF Shares 0.0%
- FHLC vs XLK · State Street Technology Select Sector SPDR ETF 0.0%
- FHLC vs VHT · Vanguard Health Care Index Fund ETF Shares 95.2%
- FHLC vs XLV · State Street Health Care Select Sector SPDR ETF 85.0%
- FHLC vs IXJ · iShares Global Healthcare ETF 70.9%
- FHLC vs IBB · iShares Biotechnology ETF 17.6%
More comparisons with XBI
- XBI vs XLV · State Street Health Care Select Sector SPDR ETF 6.3%
- XBI vs IXJ · iShares Global Healthcare ETF 5.8%
- XBI vs IHF · iShares U.S. Healthcare Providers ETF 0.0%
- XBI vs IHI · iShares U.S. Medical Devices ETF 0.0%
- XBI vs VGT · Vanguard Information Technology Index Fund ETF Shares 0.0%
- XBI vs XLK · State Street Technology Select Sector SPDR ETF 0.0%
Percentages are holdings overlap with the named fund.
Open FHLC or XBI at a brokerage
Both funds trade commission-free at major US brokerages.
Affiliate links — opening an account through these earns PlainIndex a one-time referral. Scoring is computed before any affiliate consideration; see our methodology and funding disclosure.
Holdings overlap is the sum of min(weight_a, weight_b) over positions
matched on ISIN (CUSIP fallback). Methodology: see
/methodology/.
Comparing two funds doesn't endorse swapping one for the other. Tax-lot history, account type, and personal goals matter — PlainIndex publishes data and methodology, not investment advice.